Sensitivity & Specificity

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Sensitivity = TP/(TP+FN) = how good at finding disease (columns: diseased). Specificity = TN/(TN+FP) = how good at clearing healthy. SnNOUT (Sensitive test, Negative rules OUT) / SpPIN (Specific test, Positive rules IN). Properties of the TEST, independent of prevalence. Trade-off via cut-off. Worked example. Exam tip: sens/spec are intrinsic; PPV/NPV are not.

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